Reduced thickness ---------------> ---------------> ---------------> |
 |
Low intensity <--------------- <--------------- <--------------- |
In principle, the same procedure for calculating the original values at different locations of a PET image can be applied if structural informations are available.
This is the case when an MRI is available.
If a PET/MRI couple of studies is available, co-registration and segmentation of the MRI provides for each PET voxel information about the underlying structure, which is the basis for all the published PVE-correction algorithms